Integrated stress response (ISR) activation and apoptosis through HRI kinase by PG3 and other p53 pathway-restoring cancer therapeutics September 18, 20240CommentsRead More
Dr. El-Deiry co-chairs the 15th International p53 Workshop in Philadelpha, Pennsylvania October 8-10, 2010 August 23, 20240CommentsRead MoreRead More
Dr. El-Deiry chairs AACR special conference on Cell Death Mechanisms and Cancer Therapy February 1-4, 2010 in San Diego, California August 23, 20240CommentsRead MoreRead More
Zhang, S., Zhou, L., Zhang, L., Pinho-Schwermann, M., Carneiro, B., Sedivy, J., and El-Deiry, W.S. Small molecule NSC59984 synergizes with PARP inhibitors in BRCA1 wild type ovarian cancer. 115th Annual AACR meeting, April 5-10, 2024, San Diego, CA. August 23, 20240CommentsRead More
Tian, X., and El-Deiry, W.S. Combined treatment with PG3 and Nelfinavir induced synergistic apoptosis though sustained activation of integrated stress response. 115th Annual AACR meeting, April 5-10, 2024, San Diego, CA. August 23, 20240CommentsRead More
Srinivasan, P.R., De La Cruz, A.J., Pinho-Schwermann, M., George, A., MacDonald, W.J., Zhang, S., and El-Deiry, W.S. Small molecule NSC59984 stimulates mitochondria-dependent ferroptosis and overcomes integrated stress response pro-survival signaling in pre-clinical pancreatic and colorectal cancer models. 115th Annual AACR meeting, April 5-10, 2024, San Diego, CA. August 23, 20240CommentsRead More
Tian, X., Srinivasan, P., and El-Deiry, W.S. ClpP-dependent and -independent activation of HRI kinase by small molecules. 115th Annual AACR meeting, April 5-10, 2024, San Diego, CA. August 23, 20240CommentsRead More
El-Deiry Lab presentations on p53 drug development research at 2024 American Association for Cancer Research Meeting in San Diego August 16, 20240CommentsRead More
Update from 2024 American Association for Cancer Research Meeting in San Diego August 16, 20240CommentsRead More
Dr. El-Deiry co-chairs Global Cancer Consortium’s International Conference entitled “p53 Therapeutics Mini-Symposium” attended by over 500 leading researchers world-wide. July 10, 20240CommentsPIPELINE p53-Therapeutics, Inc.Read More